自然科学版 英文版
自然科学版 英文版
自然科学版 英文版

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中南大学学报(英文版)

Journal of Central South University

Vol. 25    No. 8    August 2018

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Intraretinal layer segmentation and parameter measurement in optic nerve head region through energy function of spatial-gradient continuity constraint
CHEN Zai-liang(陈再良)1, 2, WEI Hao(魏浩)1, 2, SHEN Hai-lan(沈海澜)1, PENG Peng(彭鹏)1, 2, YUE Ke-juan(岳珂娟)1, LI Jian-feng(李建锋)3, ZOU Bei-ji(邹北骥)1, 2

1. School of Information Science and Engineering, Central South University, Changsha 410083, China;
2. Joint Laboratory of Mobile Health, Ministry of Education and China Mobile, Changsha 410083, China;
3. School of Information Science and Engineering, Jishou University, Jishou 416000, China

Abstract:For the diagnosis of glaucoma, optical coherence tomography (OCT) is a noninvasive imaging technique for the assessment of retinal layers. To accurately segment intraretinal layers in an optic nerve head (ONH) region, we proposed an automatic method for the segmentation of three intraretinal layers in eye OCT scans centered on ONH. The internal limiting membrane, inner segment and outer segment, Bruch’s membrane surfaces under vascular shadows, and interaction of multiple high-reflectivity regions in the OCT image can be accurately segmented through this method. Then, we constructed a novel spatial-gradient continuity constraint, termed spatial-gradient continuity constraint, for the correction of discontinuity between adjacent image segmentation results. In our experiment, we randomly selected 20 B-scans, each annotated three retinal layers by experts. Signed distance errors of -0.80 μm obtained through this method are lower than those obtained through the state-of-art method (-1.43 μm). Meanwhile, the segmentation results can be used as bases for the diagnosis of glaucoma.

 

Key words: surface segmentation; parameter measurement; optical coherence tomography; optic nerve head; spatial-gradient continuity constraints

中南大学学报(自然科学版)
  ISSN 1672-7207
CN 43-1426/N
ZDXZAC
中南大学学报(英文版)
  ISSN 2095-2899
CN 43-1516/TB
JCSTFT
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