自然科学版 英文版
自然科学版 英文版
自然科学版 英文版

您目前所在的位置:首页 - 期刊简介 - 详细页面

中南大学学报(英文版)

Journal of Central South University

Vol. 12    No. 1    February 2005

[PDF Download]    [Flash Online]

    

Preparation and characterization of poly(D,L-lactide) and
its porous biomaterials
ZHOU Zhong-cheng(周忠诚), RUAN Jian-ming(阮建明), HUANG Bai-yun(黄伯云),
LI Ya-jun(李亚军), ZOU Jian-peng(邹俭鹏), ZHANG Hai-bo(张海波)

State Key Laboratory of Power Metallurgy,Central South University, Changsha 410083,China

Abstract:Poly(D,L-lactide) was synthesized by indirect method from D,L-lactic acid and characterized by infrared spectrum and proton nuclear magnetic resonance. The influences of monomer purity, initiator concentration, polymerization temperature and polymerization time on the relative molecular mass of poly(D, L-lactide) were investigated. The polylactide was made into porous materials by using solvent-casting particulate-leaching method. Under the optimized conditions, polylactides with a viscosity average molecular mass up to 1.82×105are obtained and the results are fairly reproducible. Scanning electron microscope observation indicates that the sample is highly porous and well-distributed with good interconnections between pores and the pore size of porous materials is in the range from 200μm to 500μm and it can be used as scaffold for bone tissue engineering.

 

Key words: lactide; polylactic acid; tissue engineering; scaffold

中南大学学报(自然科学版)
  ISSN 1672-7207
CN 43-1426/N
ZDXZAC
中南大学学报(英文版)
  ISSN 2095-2899
CN 43-1516/TB
JCSTFT
版权所有:《中南大学学报(自然科学版、英文版)》编辑部
地 址:湖南省长沙市中南大学 邮编: 410083
电 话: 0731-88879765 传真: 0731-88877727
电子邮箱:zngdxb@csu.edu.cn 湘ICP备09001153号